Additionally, Ding et al. discovered that harmine could inhibit the proliferation and migration of breast cancer cells, as well as induce apoptosis via the downregulation of PDZ-binding motif (TAZ) and Bcl-2 protein and the upregulation of Bax protein in MDA-MB-231 and MCF-7 cells [66]. This evidence concerns the gene BCL2 and breast carcinoma.