In addition to IL11, this subcluster is associated with transcripts for MMP3, MMP1, MMP9, SERPINB2, S100A6, and CXCL8, among other genes associated with inflammation, fibrosis, and senescence, as well as endometriosis, as shown in the middle panel (subcluster 1) of Fig. 6 (and Additional file 6). The gene discussed is MMP1; the disease is endometriosis.