Compared with the transfection of the empty vector, colon cancer HT-29 cells with overexpressed NudCD1 had significantly increased mRNA levels of BUBR1 (1.154 ± 0.258 vs 2.455 ± 0.359, P < 0.05), MPS1 (1.179 ± 0.158 vs 1.671 ± 0.200, P < 0.05) and LIS1 (1.228 ± 0.220 vs 1.97 ± 0.304, P < 0.05). This evidence concerns the gene BUB1B and colonic neoplasm.