For tumours without corresponding normal tissue in TCGA, we further assessed the diversities in DYRK2 expression between them and corresponding normal tissues by GTEx dataset.We further estimated the expression difference of DYRK2 between the normal tissues and tumor tissues of DLBC (Lymphoid Neoplasm Diffuse Large B-cell Lymphoma), LGG (Brain Lower Grade Glioma), OV(Ovarian serous cystadenocarcinoma),SARC (Sarcoma),and THYM (Thymoma) (Fig. 1C, P  < 0.05). Here, DYRK2 is linked to sarcoma.