The correlation between the expression of DYRK2 and the pathological stages of cancers, including ESCA(Esophageal carcinoma),HNSC(Head and Neck squamous cell carcinoma) and LIHC(Liver hepatocellular carcinoma) were analyzed by the GEPIA2 tool (Fig. 1D, all P < 0.05). The gene discussed is DYRK2; the disease is carcinoma of esophagus.