TNF and neoplasm: Second, analyses performed on tumor lysates revealed that chemokines involved in myeloid cell migration (CCL5, CCL2, CCL4), together with inflammatory (IL-1β and TNFα) and pro-angiogenic factors (VEGF-A, VEGFR2, PDGF, Endoglin) were increased in tumors of mice fed a HFHCD (Fig. 3a).