TP53 and B-cell chronic lymphocytic leukemia: Of patients with CLL/SLL who underwent cytogenetic assessment in our study, 75%, 60.5%, and 66.5% received testing for del17p, mutated TP53, and del11q, respectively, yet only 15% of patients in the CLL/SLL population were tested for IGHV. Today, IGHV testing is more practice integrated for patients with CLL than at the start of the study in 2016; until recently, this test was only performed in clinical trials but is now becoming an important decision-making element in Europe.