CEACAM5 and rectal cancer: Univariate analysis of the changes in hematological indexes: the changes in white blood cells, neutrophils, red blood cells, and the pathological response of rectal cancer after neoadjuvant therapy were not statistically significant (P > 0.05), and the changes of lymphocytes (P = 0.001), platelet changes (P = 0.005), and CEA changes (P = 0.013) were significantly associated with pathological responses after neoadjuvant therapy for rectal cancer (Table 4).