MYC and neoplasm: However, in the si-MYC group, no difference in the ratios of the replicating cells was observed between Huh 7-WT/Bel-7404-WT and Huh 7-TM/Bel-7404-TM cells (Figure 5C–H), which further highlighted the role of MYC in the tumour-promoting effect of HBx conferred by mutation T81P/S101P/L123S.