Six other miRNA which were downregulated in IUGR groups may potentially target 378 transcripts which are enriched in many pathways including citrate cycle (TCA cycle), HIF-1 signalling pathway, ferroptosis, glycolysis/gluconeogenesis, sphingolipid metabolism, ErbB signalling pathway, PPAR signalling pathway, fatty acid elongation and biosynthesis of unsaturated fatty acids (figure 5). The gene discussed is HIF1A; the disease is fetal growth restriction.