No significant difference was found between the two groups in an initial grade of severity (13 mild and 7 moderate grades in IP vs. 9 mild and 1 moderate grade in OP) as well as signs of inflammation reaction, such as lymphocyte count (IP vs. OP: 958.4 ± 753.7 vs. 944.8 ± 237.8/μL) and serum CRP level (IP vs. OP: 4.91 ± 6.37 vs. 3.26 ± 2.89 mg/dL). This evidence concerns the gene CRP and incontinentia pigmenti.