The KM plotter analysis for the top winning TFs showed a statistically significant association between the expression levels of ZBTB16, TAL1, FOXM1, SOX17, EPAS1, KLF2, ID4, MYBL2, NR4A2, FOXF1, GATA6, HOXC6, and RFX2 with the survival of lung cancer patients (Figure 11). The gene discussed is KLF2; the disease is lung cancer.