PDE5A and cancer: In the LCII coexpression network, 18 DEGs (ABCA3, ALDH3B1, C1QTNF7, CBLC, CYP27A1, DES, FANCG, FR, FLRT3, MD4A, IGSF10, KCNT2, MAMDC2, MND1, PDE5A, RSPO1, SLC6A4, TM6SF1, and W6DC) have evidence of their deregulation in lung cancer but have not yet been associated with the acquisition of any hallmark of cancer (Supplementary Table S4).