ADAM10 and hepatocellular carcinoma: Xu et al. confirmed that hUCMSC-derived exosomal miR-451a could inhibit the EMT of hepatocellular carcinoma Hep3B and SMMC-7721 cell lines through the inhibition of ADAM10, thus increasing the paclitaxel (PTX) sensitivity of hepatocellular carcinoma cells in vitro [93].