Urine biomarkers of kidney tubular injury (KIM-1), inflammation (monocyte chemoattractant protein 1; MCP-1 and human cartilage glycoprotein-40; YKL-40), tubular health (epidermal growth factor; EGF and uromodulin; UMOD), and glomerular and tubular disease (albumin) have each been associated with CKD progression [14–19] and are known to rise, at least transiently, after AKI [20–24]. This evidence concerns the gene CHI3L1 and chronic kidney disease.