Finally, a score model for predicting the onset of HCC was constructed based on these independent risk factors and two general characteristics (age and gender) of patients: Score model = 0.009755*AFPL3 − 0.141957*Gender − 0.017824*Age (years) + 0.036840*ALB (g/L) − 0.004326*ALT (U/L) + 0.642490*(status of HBsAg) − 0.832696*(status of HBeAg), (Male equal to 1 and Female equal to 0; the status of HBsAg-positive and HBeAg-positive both equal to 1 and the status of HBsAg-negative and HBeAg-negative both equal to 0). This evidence concerns the gene GPT and hepatocellular carcinoma.