KCNQ1OT1 and neoplasm: Additionally, a recent study reported that KCNQ1OT1 participated in Yin Yang 1 (YY1)-mediated tumor-promoting effects on Triple-negative breast cancer (TNBC) through its interactions with DNMT1, in support of role of KCNQ1OT1 in TNBC (Shen et al. 2020).