Additionally, KCNQ1OT1 exerted tumor-promoting roles in colorectal carcinogenesis (Chen et al. 2020b), non-small-cell lung carcinoma (Dong et al. 2019), hepatocellular carcinoma (Xu et al. 2020), bladder cancer (Wang et al. 2019a), glioma (Ding et al. 2020), osteosarcoma (Wang et al. 2019b), gastric cancer (Wang et al. 2020) and OC (Liu et al. 2020). This evidence concerns the gene KCNQ1OT1 and hepatocellular carcinoma.