This study demonstrated that administration of intensive insulin treatment to poor glycemic control (A1c > 8.5%) T1D adults from public health system, can be optimized (reduction in A1c and an increase in TIR without an increase in hypoglycemia), using bolus calculators by intelligent glucometer (COMBO®) or mobile APP (GLIC®) became its like CSII users. This evidence concerns the gene INS and type 1 diabetes mellitus.