A recent study reported that IL-24 treatment significantly increased the levels of TGF‐β and PDGF‐B in HT‐29 epithelial cells and upregulated the levels of ECM-associated genes in CCD‐18Co colon fibroblasts, indicating that IL-24 might contribute to the development of mucosal remodeling in IBD patients [19]. This evidence concerns the gene PDGFB and inflammatory bowel disease.