The results showed that NLRP3, SIRT3, and IL-1β were mainly expressed in mesothelial cells, and the expression of SIRT3 was evidently downregulated, while the expression of NLRP3 and IL-1β was upregulated in PA tissues compared with normal peritoneal tissues (Fig. 8e–j), suggesting that rescuing SIRT3 may be a therapeutic strategy to treat postsurgical PAs. The gene discussed is SIRT3; the disease is gonorrhea.