IL1B (IL-1β) mRNA and IL1RN (IL-1RA) mRNA expression in granulocytes was higher in MPN patients than NC (Fig. 1a, b, lower panel) and PV patients showed the highest IL1B mRNA within the MPN group (Fig. 1a, b, lower panel). Here, IL1RN is linked to myeloproliferative neoplasm.