TF and Zika virus infectious disease: These results support the findings detected by RNA-seq analysis and indicate that ZIKV infection of moDCs induces transcription at only a small number of promoters and enhancers (Supplementary Figs. 2b and 3b), and that the response is highly enriched for genes involved in lipid synthesis and involves TF motifs implicated in SREBP-dependent regulation (Fig. 3c–e).