In addition, Yixing Wu’s team used gene expression profiles from public databases, and found that the expression levels of histone cluster 2 H2A family member A3(HIST2H2AA3), leucine zipper protein 6 (LUZP6) and major histocompatibility complex, class II, DR alpha (HLA-DRA) in the exosome displayed high value in distinguishing PC from both healthy people (AUC = 0.8558) and chronic pancreatitis (AUC = 0.815)[84]. This evidence concerns the gene HLA-DRA and chronic pancreatitis.