Further profiling analysis of the sorted monocyte (CD45+CD3−CD14+CD15−CD11b+CD11c+) population from APS and WBCs using the multiplex gene expression assay from Nanostring performed using the Rosalind platform found that there were 109 differentially regulated genes when comparing monocytes sorted from APS to monocytes sorted from WBCs; the top 50 differentially regulated genes are shown in Fig. 2e. Here, ITGAX is linked to autoimmune polyendocrinopathy.