Gene Ontology (GO) analysis of all significantly differentially regulated genes found that for the category of biological processes, sorted monocytes from APS had functional enrichment related to the following GO terms relevant to tissue repair: “IL-4-mediated signaling pathway and antigen processing” and “presentation of endogenous peptide via MHC class I via ER pathway, TAP-independent.” The molecular function category found enrichment in terms related to antigen processing such as TAP binding and TAP2 binding. This evidence concerns the gene IL4 and autoimmune polyendocrinopathy.