Moreover, recovery of CKS2 by lentivirus-mediated overexpression of CKS2 in CKS2-KD cells (CKS2_Rescue) restored expression of CKS2 in both RNA and protein levels (Fig. 4H, I) and rescued cancer-associated phenotypes including cell proliferation, colony formation, EdU staining and tumor xenograft growth (Fig. 4J–N). Here, CKS2 is linked to cancer.