We measured LMNA expression by RT-QPCR using oligos recognizing both lamin A and lamin C. This analysis shows that the levels of LMNA mRNA are significantly reduced in the three tumor cell lines (HeLa, A549, and MCF7), as compared to non-transformed cells (wild type, HGPS and EDMD2) (Fig. 4A). The gene discussed is LMNA; the disease is neoplasm.