Here, we sought to investigate the role of myeloid Lkb1 in lung inflammation induced by the Gram-positive bacterial wall component and TLR2 agonist lipoteichoic acid (LTA) [14] and viable Spneu. For this we used myeloid-specific Lkb1 deficient mice and well-established mouse models of an airway LTA challenge and pneumococcal pneumonia. The gene discussed is STK11; the disease is pneumococcal pneumonia.