This 12-gene assay is used to obtain a score based on the expression of 7 cancer-related genes (Ki67, AURKA/STK15, BIRC5/survivin, CCNB1, MYBL2, PGR, and GSTM1) and 5 normalizing reference genes (ACTB, GAPDH, RPLPO, GUS, and TFRC) [27]. Here, AURKA is linked to cancer.