Fecal MPO—a lysosomal protein found in neutrophils that is used as a marker of oxidative stress induced by inflammatory bowel disease (IBD) and EE, and is predictive of subsequent growth faltering in young children27,29,59,60— had an inverse association with sCD40L that was larger and more statistically significant than that of mannitol, as did proline, another documented predictor of poor growth and oxidative damage.27 This evidence concerns the gene MPO and inflammatory bowel disease.