A variety of GPCRs related with reproductive function have been reported to be implicated in the oncogenesis and progression of prostate cancer, including gonadotropin-releasing hormone (GnRH) receptor, luteinizing hormone receptor, follicle-stimulating hormone receptor, relaxin receptor, ghrelin receptor, and kisspeptin receptor [62]. The gene discussed is LHCGR; the disease is prostate carcinoma.