A 10% increase in Cystatin-C, measured at visit 1, was associated with 13% increase in the odds ratios of diabetes (log Cystatin-C OR visit-1 = 3.69, p<0.001) at visit 1, 11% at visit 2 (OR visit-2 = 3.00, p<0.001), and 9% at visit 3 (OR visit-3 = 2.45, p<0.001). The gene discussed is CST3; the disease is diabetes mellitus.