Kv3.1 and Kv3.2 potassium channels are highly expressed on fast-spiking GABA interneurons including those that express parvalbumin in the striatum (Chow et al. 1999; Rudy and McBain 2001), and Kv3 knockout mice show locomotor hyperactivity, a behavioural phenotype associated with preclinical models of schizophrenia (Espinosa et al. 2004; Kokkinou et al. 2021). Here, KCNC2 is linked to schizophrenia.