IFNG and infection: Inborn errors of IFN-γ immunity can also underlie infections caused by Mycobacterium tuberculosis (M.tb), which is ≥1,000 times more virulent than BCG (Boisson-Dupuis, 2020; Boisson-Dupuis and Bustamante, 2021; Ogishi et al., 2021; Casanova and Abel, 2022), and a few other intramacrophagic pathogens, including bacteria (e.g., Salmonella), parasites (e.g., Leishmania), and fungi (e.g., Histoplasma; Arias et al., 2017; Bustamante, 2020; Bustamante et al., 2014; de Beaucoudrey et al., 2010; Parvaneh et al., 2017; Tan et al., 2016; van de Vosse et al., 2013).