In a retrospective analysis of the AENEAS group focusing on anti-MDA5+ patients as a whole [7▪▪], 89% of patients were diagnosed with myositis (dermatomyositis 43%, CADM 31%, polymiositis 5%, overlap myositis 11%); interestingly, the remainder 10% was diagnosed with interstitial pneumonia with autoimmune features (IPAF), not satisfying any other classification criterion. The gene discussed is IFIH1; the disease is myositis disease.