TLR1 and acute myeloid leukemia: As a proof of concept, we tested if wecould distinguish phenotypes of THP-1 cells, a model of human monocytesderived from AML,37 upon stimulation witha number of pro-inflammatory stimuli, namely, LPS, Pam2CSK4, Pam3CSK4, polyinosinic:polycytidylicacid (poly(I:C)), and polyadenylic–polyuridylic acid (poly(A:U)),which activate TLR4, TLR2/6, TLR1/2, and TLR3, respectively, as wellas interferon-γ (IFN-γ).