PVT1 and triple-A syndrome: In abdominal aortic aneurysm (AAA) tissues, lncRNA PVT1, and NCK-associated protein 1-like (NCKAP1L) expression was elevated and induced in vitro in AAA models, while miR-3127-5p showed the opposite trend, and lncRNA PVT1 acted as a sponge for miR-3127-5p to regulate NCKAP1L expression, inhibit VSMC proliferation, and induce apoptosis (84).