KLRK1 and hepatocellular carcinoma: In Sun’s study, the second generation human NKG2D CAR-T cells efficiently eliminated the NKG2DLs-expressing HCC cell in vitro, whereas they less efficiently killed NKG2DL-silenced or -negative cells; The subcutaneous xenograft model further illuminated that T cells expressing the NKG2D CAR effectively suppress tumor growth.