UBE2D3, APC, SMAD1, BMPR1A, CTNNB1, and MAP3K7 in TGF-β1 signaling pathway, showed positive correlation with m7G scores through most cancer types (≥30 cancers), while ADAM17, HDAC2, MAML1, CTNNB1, SKP2, MYC and CUL1 in Wnt/β-catenin signaling positively correlated with m7G scores among most cancer types (≥30 cancers). The gene discussed is ADAM17; the disease is cancer.