Among that, three genes (PRCC, PYGO2, and MSTO1) were related to Child-pugh grade; 15 genes were related to liver fibrosis; 31 genes were related to histologic tumor grade; 10 genes were related to AJCC stage; 19 genes were related to family history of cancers; and 9 genes were related to tumor recurrence (Figure 5A). The gene discussed is PYGO2; the disease is cancer.