More drugs have high sensitivities for BC patients in cluster 2, including AZD.2281(Olaparib), AZD6244(Selumetinib), Bosutinib, CGP.60474(PKC inhibitor), CI.1040 (MEK inhibitor), Etoposide, GDC.0449(Vismodegib), Gefitinib, Gemcitabine, JNK.9L (JNK inhibitor), Pyrimethamine, Roscovitine, and Temsirolimus. The gene discussed is PRRT2; the disease is breast cancer.