For instance, He ZJ screened 15 key genes (CXCR6, SELL, P2RY13, GNG8, OMD, ABI3BP, OGN, FBLN1, LOXL1, ELN, CTSK, HGF, SH3GL3, F13A1, and GTPBP2) based on the mRNA-seq sequencing data and the stem cell index established according to TCGA-ACC mRNA profiles. The gene discussed is SH3GL3; the disease is adrenal cortex carcinoma.