Finally, we proposed lncRNA/miRNA pairs; hsa-miR-124-3p/KCNQ1OT1, hsa-miR-124-3p/NEAT1, and hsa-miR-124-3p/XIST, all of which are expressed in the brain, as new candidate biomarkers for the occurrence of DM and AD simultaneously. The gene discussed is KCNQ1OT1; the disease is Alzheimer disease.