Studies have also indicated that increased PSPH expression was observed in many cancers including breast cancer, colorectal cancer, gastric cancer, hepatocellular carcinoma, melanoma, and non-small cell lung cancer (Liao et al., 2019; Rawat et al., 2021; Sun et al., 2016; D'Arcy et al., 2015; Allard et al., 2012; Sato et al., 2017; Sun et al., 2015). The gene discussed is PSPH; the disease is cancer.