Neither the linear associations of weight change with dementia across the three fifths with greatest weight loss, nor the associations of the fifth with greatest weight loss versus other fifths of weight change with dementia showed heterogeneity by age at final follow‐up, period of follow‐up, or APOE genotype (all P‐value ≥ .05, Supplementary Information Figure S4). This evidence concerns the gene APOE and dementia.