BNIP3 and lung adenocarcinoma: To further explore the role of BNIP3 in lung cancer cells, five pairs of human lung cancer tissues and their paraneoplastic tissues were incubated with BNIP3 as primary antibody, and the results of immunohistochemistry showed that BNIP3 was highly expressed in lung adenocarcinoma compared with normal tissues (Figure 9(a)).