Taraxerol or aqueous extracts (protocatechuic acid, caffeic acid, coumaric acid, ferulic acid, etc.)also improve the inflammatory symptoms of human umbilical vein endothelial cells by inhibiting the expression of NF-κB pathway and related inflammatory factors and adhesion factors, and it can be used to treat chronic diseases such as atherosclerosis and mastitis (Hu et al., 2017). This evidence concerns the gene NFKB1 and mastitis.