HDAC4 and diabetic kidney disease: Moreover, many researches have also revealed the effects of protein tyrosine phosphatase 1B, resveratrol, ursodeoxycholic acid and 4-phenylbutyrate as well as histone deacetylase 4 on the autophagic process of podocytes in DKD models (Wang et al., 2014; Cao et al., 2016; Huang et al., 2017; Ito et al., 2017).