Hyperglycemia caused by a deficiency in insulin production by the β-cells of the pancreas is known as Type 1 diabetes mellitus (T1DM) and due to insufficiency of insulin production in the face of insulin resistance or β-cells dysfunction is Type 2 diabetes mellitus (T2DM) (Care, 2013; Tran et al., 2020). Here, INS is linked to type 1 diabetes mellitus.