For example, myricetin induces apoptosis and regulates JNK-mediated autophagy in SK-BR-3 human breast cancer cells through the MAPK pathway, while it induces cellular oxidative stress and produces intracellular ROS through the Fenton reaction in triple negative breast cancer cells (Knickle et al., 2018). The gene discussed is MAPK8; the disease is triple-negative breast carcinoma.