Optical coherence tomography; diabetic macular edema; fully automated detection; visual field thresholds; deep learning algorithm; anti-VEGF therapy; treat-and-extend; SD-OCT; geographic atrophy; neural network; artificial intelligence (AI); machine learning (ML); deep learning (DL); automated screening; prognosis and prediction; personalized healthcare (PHC). The gene discussed is VEGFA; the disease is diabetic macular edema.