MRC1 and exstrophy-epispadias complex: In presence of young women with Stage IA G1 EEC or AEH, strongly persuaded to preserve their fertility and candidates for conservative treatment (36–38), identifying MMR-deficient patients and, possibly, patients with LS could also be essential in guiding adequate counseling: indeed, our data show how these patients tend to have a worse outcome than MMR-proficient patients (39, 40).