In contrast, TLR2 inhibition resulted in significant decreases in NF-κB/AP-1-dependent SEAP activity at 72 h and 120 h for macrophages cultured on the lysate-conditioned TeflonTM AF surfaces (p < 0.05, compared to the uninhibited Lysate condition). This evidence concerns the gene NFKB1 and atrial fibrillation.